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Senior Manager/ Associate Director GMP Quality
<div class="content-intro"><p><strong>J<span data-olk-copy-source="MessageBody">oin Us in Tackling Autoimmune Disease at Its Root</span></strong></p> <p><span data-olk-copy-source="MessageBody">At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide.</span></p> <p>When you join Vor, you’re not just working on a medicine. You’re part of a mission to redefine the future of autoimmune care.</p> <p><strong data-olk-copy-source="MessageBody">Why Work at Vor?</strong></p> <p>Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.</p> <p>Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond.</p> <p>Innovation: Work on a platform with potential beyond one indication — a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren’s syndrome.</p> <p>Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies.</p> <p> </p></div><p><strong><span data-contrast="auto">Location: Boston, MA preferred but can be remote</span></strong></p> <p></p> <p>Position: Sr. Manager/Associate Director GMP Quality</p> <p>Reporting to: Director, GMP Quality</p> <p>The position will be responsible for day-to-day operational support ensuring compliance with current Good Manufacturing Practices (cGMP) for all clinical and commercialization activities. This role will perform GMP operations, from clinical trial material manufacturing, QC testing, distribution and validation. This role will assist in the transition into commercial-scale production. Partner and collaborate with internal and external teams, ensuring alignment on quality standards and the timely execution of all deliverables.</p> <p>The ideal candidate will possess a strong combination of strategic thinking and hands-on expertise in GMP Quality operations within the biotech industry.</p> <p>Key Responsibilities</p> <p>· GMP Quality Oversight: Point of contact for GMP Quality Operations function for clinical manufacturing, distribution, validation and commercialization activities. Support tech transfer as applicable. Ensure all activities comply with relevant regulatory guidelines (FDA, EMA, ICH, etc.) and Quality Agreements.</p> <p>· Regulatory Compliance: Support regulatory inspections and audits (FDA, EMA, etc.) as assigned.</p> <p>· Supplier & CMO Management: Provide quality oversight of external manufacturers, contract manufacturing organizations (CMOs), and suppliers to ensure compliance with GMP standards.</p> <p>· Quality Systems and Compliance: Provide oversight on investigations related to deviations and product quality issues, ensuring timely resolution, root cause analysis and CAPA implementation. Point of contact for 3rd party supplier & CMO quality events. Responsible for inputting quality documents into the eQMS.</p> <p>· Inspection Readiness: Support functional groups to perform identified inspection readiness activities and provide oversight of vendor inspection readiness activities.</p> <p>· Documentation Management: Author, review and approval of GMP documentation, including batch records, release specifications, QC data, protocols, validation reports, etc.</p> <p>· Risk Management: Identify and mitigate quality risks within clinical development and pre-commercialization activities.</p> <p>· Cross-functional Collaboration: Partner with CMC, Supply Chain, Commercial and Regulatory Affairs teams to ensure quality compliance throughout the product lifecycle from clinical trials to commercial manufacturing.</p> <p>Qualifications</p> <p>· Education:</p> <p>o Bachelor's degree in Life Sciences, Engineering, or a related field.</p> <p>· Experience:</p> <p>o Minimum 8 years of experience in quality operations, quality assurance, or GMP manufacturing within the biotechnology or pharmaceutical industry.</p> <p>o Experience with Phase 3 clinical trials and the transition to commercialization is highly preferred.</p> <p>· Skills & Competencies:</p> <p>o Expertise in GMP, regulatory requirements, and industry best practices (FDA, EMA, ICH).</p> <p>o Ability to collaborate with cross-functional teams and complex initiatives.</p> <p>o Excellent knowledge of quality systems, documentation, and compliance management.</p> <p>o Exceptional problem-solving, troubleshooting, and analytical skills.</p> <p>o Strong communication and presentation skills, both written and verbal.</p> <p>o Ability to work effectively in a remote, fast-paced, and evolving environment</p> <p></p> <div> </div> <div id="x_x_x_Signature"></div> <p> </p> <p><em>The salary range for the Senior Manager GMP Quality<span data-olk-copy-source="MessageBody"> </span>is expected to be between $160,000 and $175,000 per year. Individual pay may vary based on multiple factors including but not limited to relevant job-related skills, experience, education or training, market factors, and work location.</em></p> <p><em>The salary range for the Associate Director GMP Quality<span data-olk-copy-source="MessageBody"> </span>is expected to be between $175,000 and $200,000 per year. Individual pay may vary based on multiple factors including but not limited to relevant job-related skills, experience, education or training, market factors, and work location.</em></p> <p> </p><div class="content-conclusion"><p><span data-olk-copy-source="MessageBody">At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well-being so you can thrive at work and beyond.</span></p> <p class="p1">As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.</p> <p>Please visit our website at https://www.vorbio.com/ for more information.</p></div>